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Anti-Mouse IFNγR/CD119 Antibody (GR-20)

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Catalog No. T9901A-1222
Alias GR-20

Anti-Mouse IFNγR/CD119 Antibody (GR-20) is a rat-derived IgG2a κ inhibitory antibody that binds specifically to the α chain of mouse IFNγR (CD119) to block the interaction between IFNγ and CD119, thereby inhibiting the IFNγ-mediated signaling pathway. Anti-Mouse IFNγR/CD119 Antibody (GR-20) can be widely applied to relevant research in the fields of cancer, infectious diseases, inflammatory diseases and immunology, such as the research on the pathogenesis of melanoma and the research on genital tract inflammation induced by Chlamydia trachomatis infection .

Anti-Mouse IFNγR/CD119 Antibody (GR-20)

Anti-Mouse IFNγR/CD119 Antibody (GR-20)

😃Good
Catalog No. T9901A-1222Alias GR-20
Anti-Mouse IFNγR/CD119 Antibody (GR-20) is a rat-derived IgG2a κ inhibitory antibody that binds specifically to the α chain of mouse IFNγR (CD119) to block the interaction between IFNγ and CD119, thereby inhibiting the IFNγ-mediated signaling pathway. Anti-Mouse IFNγR/CD119 Antibody (GR-20) can be widely applied to relevant research in the fields of cancer, infectious diseases, inflammatory diseases and immunology, such as the research on the pathogenesis of melanoma and the research on genital tract inflammation induced by Chlamydia trachomatis infection .
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$163InquiryInquiry
5 mg$538InquiryInquiry
10 mgPreferentialInquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Mouse IFNγR/CD119 Antibody (GR-20) is a rat-derived IgG2a κ inhibitory antibody that binds specifically to the α chain of mouse IFNγR (CD119) to block the interaction between IFNγ and CD119, thereby inhibiting the IFNγ-mediated signaling pathway. Anti-Mouse IFNγR/CD119 Antibody (GR-20) can be widely applied to relevant research in the fields of cancer, infectious diseases, inflammatory diseases and immunology, such as the research on the pathogenesis of melanoma and the research on genital tract inflammation induced by Chlamydia trachomatis infection .
In vitro
Treatment with Anti-Mouse IFNγR/CD119 Antibody (GR-20) for 1 hour downregulates the expression level of the non-classical MHC molecule Qa-1b in B16 melanoma cells [1].
In vivo
Intraperitoneal administration of Anti-Mouse IFNγR/CD119 Antibody (GR-20) (200 μg per dose, with the first dose administered 1 day prior to Chlamydia trachomatis infection and subsequent doses given every other day) induces extensive genital tract inflammation and tissue damage in infected mice [2].
SynonymsGR-20
Clone
GR-20
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIFNγR/CD119
Chemical Properties
Molecular Weight150 kDa
Antibody Information
IsotypeRat IgG2a kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | Lyophilized powder: -20~-80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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