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Sacituzumab govitecan

Name: Sacituzumab govitecan
Brand: TargetMol
SKU: T77824
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77824Cas No. 1491917-83-9

Alias IMMU-132

Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.

Sacituzumab govitecan

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Purity: 98.4% (SEC-HPLC)

Catalog No. T77824Alias IMMU-132Cas No. 1491917-83-9

Pack Size	Price	Availability
1 mg	$455	In Stock
5 mg	$1,360	In Stock
10 mg	$1,830	2-4 weeks
25 mg	$2,730	2-4 weeks

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Concentration:2.43 mg/mL

Purity:98.4% (SEC-HPLC)

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COA SEC-HPLC

Product Introduction

Bioactivity

Description	Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.
In vivo	Sacituzumab govitecan administered at a dose of 17.5 mg/kg twice weekly for four consecutive weeks showed significant antitumor effects in mice bearing human gastric cancer xenograft tumors. [1]
Synonyms	IMMU-132

Chemical Properties

Molecular Weight	160 KDa (Approximately)
Cas No.	1491917-83-9

Storage & Solubility Information

Storage	store at low temperature \| Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: 20 mg/mL, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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