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Sacituzumab govitecan (Synonyms: IMMU-132)

Catalog No. T77824 Copy Product Info
Purity: 95%
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Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.

Sacituzumab govitecan

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Catalog No. T77824
Synonyms IMMU-132

Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.

Sacituzumab govitecan
Cas No. 1491917-83-9
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$455In StockIn Stock
5 mg$1,360-In Stock
10 mg$1,830-In Stock
25 mg$2,730-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent to Yellow
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Product Introduction

Bioactivity
Description
Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.
In vivo
Sacituzumab govitecan administered at a dose of 17.5 mg/kg twice weekly for four consecutive weeks showed significant antitumor effects in mice bearing human gastric cancer xenograft tumors. [1]
SynonymsIMMU-132
Reactivity
Human
Verified Activity
Immobilized Human TROP2 Protein (ECD, His) at 2 μg/mL (30 μL/well) can bind Sacituzumab govitecan. The EC50 is 0.005813 μg/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1 EU/mg
Related Conjugates and Formulations
Conjucates
SN38
Antigen Details
Uniprot ID
TargetTROP-2
Chemical Properties
Molecular Weight148.74 kDa
Cas No.1491917-83-9
Antibody Information
IsotypeHuman IgG1-REM kappa
Recommended Isotype Control
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 20.00 mg/mL, Sonication is recommended.

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