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Sacituzumab govitecan
(Synonyms: IMMU-132) Copy Product Info
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Synonyms: IMMU-132
Catalog No. T77824 Copy Product Info
Purity: 95%
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Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.
Sacituzumab govitecan
Cas No. 1491917-83-9
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $455 | In Stock | In Stock | |
| 5 mg | $1,360 | - | In Stock | |
| 10 mg | $1,830 | - | In Stock | |
| 25 mg | $2,730 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent to Yellow
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| Description | Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer. |
| In vivo | Sacituzumab govitecan administered at a dose of 17.5 mg/kg twice weekly for four consecutive weeks showed significant antitumor effects in mice bearing human gastric cancer xenograft tumors. [1] |
| Synonyms | IMMU-132 |
| Reactivity | Human |
| Verified Activity | Immobilized Human TROP2 Protein (ECD, His) at 2 μg/mL (30 μL/well) can bind Sacituzumab govitecan. The EC50 is 0.005813 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1 EU/mg |
| Conjucates | SN38 |
| Uniprot ID | |
| Target | TROP-2 |
| Molecular Weight | 148.74 kDa |
| Cas No. | 1491917-83-9 |
| Isotype | Human IgG1-REM kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: 20.00 mg/mL, Sonication is recommended. |
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Related Tags: Sacituzumab govitecan in vivo | Sacituzumab govitecan molecular weight
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