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Sacituzumab govitecan

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Catalog No. T77824Cas No. 1491917-83-9
Alias IMMU-132

Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.

Sacituzumab govitecan

Sacituzumab govitecan

😃Good
Hot
Catalog No. T77824Alias IMMU-132Cas No. 1491917-83-9
Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$455In StockIn Stock
5 mg$1,3607-10 days7-10 days
10 mg$1,8307-10 days7-10 days
25 mg$2,7307-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.4% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.
In vivo
Sacituzumab govitecan administered at a dose of 17.5 mg/kg twice weekly for four consecutive weeks showed significant antitumor effects in mice bearing human gastric cancer xenograft tumors. [1]
SynonymsIMMU-132
Reactivity
Human
Verified Activity
Immobilized Human TROP2 Protein (ECD, His) at 2 μg/mL (30 μL/well) can bind Sacituzumab govitecan. The EC50 is 0.005813 μg/mL.
verifiedActivity
Application
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin< 1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetTROP-2
Chemical Properties
Molecular Weight160 KDa (Approximately)
Cas No.1491917-83-9
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 20 mg/mL, Sonication is recommended.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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