c-1

Butyric acid-13C-1 is the 13C-labeled form of Butyric acid. Butyric acid functions as an HDAC inhibitor with demonstrated antitumor properties.

5-Aminolevulinic acid-13C-1 (5-ALA-13C-1) hydrochloride is the 13C-labeled form of 5-Aminolevulinic acid hydrochloride. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) serves as an intermediate in the biosynthesis of heme within the body and acts as a precursor to tetrapyrroles.

L-Aspartic acid-13C-1 is the deuterated form of L-Aspartic acid. L-Aspartic acid, an amino acid, has been identified as a precursor active molecule for the delivery of colon-specific active compounds.

L-Ascorbic acid-13C-1 is a 13C-labeled version of L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), known as an electron donor, functions as an endogenous antioxidant. It selectively inhibits Cav3.2 channels with an IC50 value of 6.5 μM. Additionally, L-Ascorbic acid acts as a promoter of collagen deposition and an inhibitor of elastin formation.

Cytidine-13C-1 is a 13C-labeled form of cytidine, which is a pyrimidine nucleoside and a component of RNA. It acts as a precursor to uridine and plays a role in controlling the glutamate-glial cycle, influencing phospholipid metabolism in the brain, catecholamine synthesis, and mitochondrial function.

Lactate-13C-1 sodium (20% in water) is a 13C-labeled form of lactate sodium. As a product of glycogen breakdown and glycolysis, lactate (lactic acid) sodium plays a role in various biochemical processes.

D-Glucose-13C-1 is a 13C-labeled form of D-Glucose. D-Glucose (Glucose) is a monosaccharide and an essential carbohydrate in biological systems. It serves as a sweetener for carbohydrates, is a vital component of general metabolism, and acts as a critical signaling molecule related to cellular metabolic status and responses to biotic and abiotic stress.

NH-bis(C1-Boc) is an uncleavable linker used for antibody-drug conjugates (ADC).

Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal synaptophysin level in mice, plus demonstrates estrogen-like activity.

Acid-C1-PEG5-Boc, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-O-C1-NHS ester, an alkyl/ether-based PROTAC linker, is utilized in PROTAC synthesis.

Sinocrassoside C1 is the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides

NH2-PEG6-C1-Boc (H2N-PEG6-CH2COOtBu) is a PEG-based PROTAC linker. NH2-PEG6-C1-Boc can be used in the synthesis of PROTACs.

2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker used in the synthesis of PROTACs[1].

Aeide-C1-NHS ester, an alkyl/ether-based PROTAC linker, finds utility in the synthesis of PROTACs[1].

C-NH-Boc-C-Bis-(C1-PEG1-PFP), a polyethylene glycol (PEG)-derived PROTAC linker, is utilized in the synthesis of PROTACs [1].

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

Biotin-C1-PEG3-C3-amine (TFA) is a polyethylene glycol (PEG) linker essential for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PEG-based PROTAC linker used in the synthesis of various PROTACs, including PROTAC SGK3 degrader-1. PROTACs consist of two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, while the other specifically interacts with the target protein, enabling selective degradation of target proteins via the intracellular ubiquitin-proteasome system[1].

Boc-C1-PEG3-C4-OH is an Alkyl/ether-based PROTAC linker used in the synthesis of PROTACs, characterized by their structure of two distinct ligands tethered by a linker, with one ligand binding to an E3 ubiquitin ligase and the other to the target protein, facilitating targeted protein degradation through the ubiquitin-proteasome system [1].

Nutlin-C1-amido-PEG4-C2-N3 is a novel ligand-linker conjugate for the E3 ligase, incorporating the MDM2 ligand from Nutlin 3 and a 4-unit PEG linker. This compound is specifically designed for use in PROTAC technology.

Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derivative of Estrone that specifically binds to estrogen receptor α (ERα). With a linker, it complexes with the cIAP1 ligand Bestatin, forming SNIPER[1].

NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker used for PROTAC synthesis[1].

PDP-C1-Ph-Val-Cit is a cleavable ADC linker used in antibody-drug conjugates (ADCs).