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Anti-CLEC10A Antibody (6H404) is a Rabbit antibody targeting CLEC10A. Anti-CLEC10A Antibody (6H404) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-CLEC10A Antibody (6H404) is a Rabbit antibody targeting CLEC10A. Anti-CLEC10A Antibody (6H404) can be used in ELISA. |
Alias | MGL, HML2, HML, C-type lectin domain family 10, member A, CLECSF14, CLECSF13, CD301 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 6H404 |
Reactivity | Mouse |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CLEC10A / MGL1 / CD301 (rM CLEC10A / MGL1 / CD301; TMPY-02405; NP_001191181.1; Gln58-Ser305). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse CLEC10A / MGL1 / CD301 Protein (TMPY-02405) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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