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Anti-COMMD9 Antibody (2T433)
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Catalog No. TMAY-02755
Alias HSPC166, COMM domain containing 9
Anti-COMMD9 Antibody (2T433) is a Rabbit antibody targeting COMMD9. Anti-COMMD9 Antibody (2T433) can be used in ELISA.
Anti-COMMD9 Antibody (2T433)
Anti-COMMD9 Antibody (2T433)
😃Good
Catalog No. TMAY-02755Alias HSPC166, COMM domain containing 9
Anti-COMMD9 Antibody (2T433) is a Rabbit antibody targeting COMMD9. Anti-COMMD9 Antibody (2T433) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-COMMD9 Antibody (2T433) is a Rabbit antibody targeting COMMD9. Anti-COMMD9 Antibody (2T433) can be used in ELISA. |
| Alias | HSPC166, COMM domain containing 9 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2T433 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human COMMD9 (rh COMMD9; TMPY-03505; Q9P000-1; Met1-Lys198). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | COMMD9 is a COMM domain-containing or COMMD protein. COMMD family is comprised of ten members which are widely conserved throughout evolution and share certain functional properties. They represent a recently discovered set of evolutionarily conserved factors characterized by the presence of a defining carboxy-terminal motif. COMMD protein functions in the control of the transcription factor NFkappaB. NFkappaB plays a critical role in a number of homeostatic processes in multicellular organisms, including the regulation of immunity and cell survival. COMMD proteins inhibit NFkappaB mediated gene expression, and recent mechanistic studies have revealed that COMMD1 controls the ubiquitination of NFkappaB subunits, an event linked to transcriptional termination. COMMD1 binds to a multimeric ubiquitin ligase containing Elongins B/C, Cul2 and SOCS1 (ECS( SOCS1)). In this complex, COMMD1 facilitates the binding of NFkappaB subunits to the ligase, thereby promoting their ubiquitination and degradation. Additional insights gained from these studies indicate that COMMD proteins likely play a broader role in cellular homeostasis through their participation in the ubiquitination pathway. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human COMMD9 protein (TMPY-03505) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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