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Anti-ADAM15 Antibody (5M69)
😃Good
Catalog No. TMAY-00936
Alias metargidin, MDC15, ADAM metallopeptidase domain 15
Anti-ADAM15 Antibody (5M69) is a Mouse antibody targeting ADAM15. Anti-ADAM15 Antibody (5M69) can be used in ELISA,FCM.
Anti-ADAM15 Antibody (5M69)
Anti-ADAM15 Antibody (5M69)
😃Good
Catalog No. TMAY-00936Alias metargidin, MDC15, ADAM metallopeptidase domain 15
Anti-ADAM15 Antibody (5M69) is a Mouse antibody targeting ADAM15. Anti-ADAM15 Antibody (5M69) can be used in ELISA,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ADAM15 Antibody (5M69) is a Mouse antibody targeting ADAM15. Anti-ADAM15 Antibody (5M69) can be used in ELISA,FCM. |
| Alias | metargidin, MDC15, ADAM metallopeptidase domain 15 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5M69 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of human ADAM15 expression on HeLa cells. Cells were stained with purified anti-Human ADAM15, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | ELISA,FCM |
| Recommended Dose | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ADAM15 (rh ADAM15; TMPY-00961; NP_997074.1; Met 1-Thr 696). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different tissues and cell types. Members of this family contain an amino-terminal metalloprotease domain followed by a disintegrin domain, a cysteine-rich region and a membrane proximal EGF-like domain. The disintegrin domain of ADAM15/metargidin contains an RGD tripeptide sequence, suggesting that it may potentially interact with the integrin family of proteins. ADAM15 is a transmembrane multi-domain proteins implicated in proteolysis, cell-cell and cell-matrix interactions in various disease conditions. There is also evidence supporting a role for ADAM15 in angiogenesis and angioinvasion of tumor cells, which are critical for unrestrained tumor growth and metastatic spread. Given its diverse functions, ADAM15 may represent a pivotal regulatory component of tumor progression, an important target for therapeutic intervention, or emerge as a biomarker of disease progression. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human ADAM15 protein (TMPY-00961) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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