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Anti-ADAM15 Antibody (5M69) (Synonyms: metargidin, MDC15, ADAM metallopeptidase domain 15)

Catalog No. TMAY-00936 Copy Product Info
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Anti-ADAM15 Antibody (5M69) is a Mouse antibody targeting ADAM15. Anti-ADAM15 Antibody (5M69) can be used in ELISA,FCM.

Anti-ADAM15 Antibody (5M69)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00936
Synonyms metargidin, MDC15, ADAM metallopeptidase domain 15

Anti-ADAM15 Antibody (5M69) is a Mouse antibody targeting ADAM15. Anti-ADAM15 Antibody (5M69) can be used in ELISA,FCM.

Anti-ADAM15 Antibody
(5M69)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$697-10 days7-10 days
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ADAM15 Antibody (5M69) is a Mouse antibody targeting ADAM15. Anti-ADAM15 Antibody (5M69) can be used in ELISA,FCM.
Synonymsmetargidin, MDC15, ADAM metallopeptidase domain 15
Ig Type
Mouse IgG1
Clone
5M69
Reactivity
Human
Specificity
Human ADAM15
No cross-reactivity in ELISA with
Mouse ADAM9
Mouse ADAM15
Human cell lysate (293 cell line)
Verified Activity
Flow cytometric analysis of human ADAM15 expression on HeLa cells. Cells were stained with purified anti-Human ADAM15, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
Recommended Dose
ELISA: 1:1000-1:2000; FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ADAM15 (rh ADAM15; TMPY-00961; NP_997074.1; Met 1-Thr 696). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different tissues and cell types. Members of this family contain an amino-terminal metalloprotease domain followed by a disintegrin domain, a cysteine-rich region and a membrane proximal EGF-like domain. The disintegrin domain of ADAM15/metargidin contains an RGD tripeptide sequence, suggesting that it may potentially interact with the integrin family of proteins. ADAM15 is a transmembrane multi-domain proteins implicated in proteolysis, cell-cell and cell-matrix interactions in various disease conditions. There is also evidence supporting a role for ADAM15 in angiogenesis and angioinvasion of tumor cells, which are critical for unrestrained tumor growth and metastatic spread. Given its diverse functions, ADAM15 may represent a pivotal regulatory component of tumor progression, an important target for therapeutic intervention, or emerge as a biomarker of disease progression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human ADAM15 protein (TMPY-00961)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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