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L-Cystathionine

Name: L-Cystathionine
Brand: TargetMol
SKU: T10939L
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10939LCas No. 56-88-2

Alias ZINC1532680, L-(+)-Cystathionine, Cystathionine, L-, Cystathionine

L-Cystathionine (Cystathionine, L-) is a key nonprotein amino acid related to metabolic conditions of sulfur-containing amino acids. L-Cystathionine can be used in studies about cardiovascular protection.

L-Cystathionine

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Purity: 98.00%

Catalog No. T10939LAlias ZINC1532680, L-(+)-Cystathionine, Cystathionine, L-, CystathionineCas No. 56-88-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$39	-	In Stock
5 mg	$98	-	In Stock
10 mg	$142	-	In Stock
25 mg	$236	-	In Stock
50 mg	$348	-	In Stock
100 mg	$518	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.00%

Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	L-Cystathionine (Cystathionine, L-) is a key nonprotein amino acid related to metabolic conditions of sulfur-containing amino acids. L-Cystathionine can be used in studies about cardiovascular protection.
In vitro	L-Cystathionine protects against homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells. l-Cystathione reduces mitochondrial superoxide anion production and Bax expression and inhibits its translocation to mitochondria, increases mitochondrial membrane potential, inhibits the opening of mitochondrial permeability transition pores, inhibits cytochrome c leakage from mitochondria into the cytoplasm, and downregulates caspase-9 and caspase-3 activity [1].
Synonyms	ZINC1532680, L-(+)-Cystathionine, Cystathionine, L-, Cystathionine

Chemical Properties

Molecular Weight	222.26
Formula	C₇H₁₄N₂O₄S
Cas No.	56-88-2
Smiles	N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O
Relative Density.	1.43g/cm3

Storage & Solubility Information

Storage

store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 1.56 mg/mL (7.02 mM), Sonication and heating are recommended.

DMSO: < 1 mg/mL (insoluble), Sonication is recommended.

1M NaOH: 52 mg/mL (233.96 mM)

Solution Preparation Table

H2O/1M NaOH

	1mg	5mg	10mg	50mg
1 mM	4.4992 mL	22.4962 mL	44.9924 mL	224.9618 mL
5 mM	0.8998 mL	4.4992 mL	8.9985 mL	44.9924 mL

1M NaOH

	1mg	5mg	10mg	50mg
10 mM	0.4499 mL	2.2496 mL	4.4992 mL	22.4962 mL
20 mM	0.2250 mL	1.1248 mL	2.2496 mL	11.2481 mL
50 mM	0.0900 mL	0.4499 mL	0.8998 mL	4.4992 mL
100 mM	0.0450 mL	0.2250 mL	0.4499 mL	2.2496 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc