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Anti-MICA Antibody (3K607) (Synonyms: PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250||...)

Catalog No. TMAY-02316 Copy Product Info
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Anti-MICA Antibody (3K607) is a Mouse antibody targeting MICA. Anti-MICA Antibody (3K607) can be used in ELISA,FCM.

Anti-MICA Antibody (3K607)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02316
Synonyms PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2

Anti-MICA Antibody (3K607) is a Mouse antibody targeting MICA. Anti-MICA Antibody (3K607) can be used in ELISA,FCM.

Anti-MICA Antibody
(3K607)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MICA Antibody (3K607) is a Mouse antibody targeting MICA. Anti-MICA Antibody (3K607) can be used in ELISA,FCM.
SynonymsPERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2
Ig Type
Mouse IgG1
Clone
3K607
Reactivity
Human
Specificity
Human MICA
Verified Activity
Flow cytometric analysis of Human MICA expression on HeLa cells. Cells were stained with purified anti-Human MICA, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
Recommended Dose
ELISA: 1:1000-1:2000; FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICA (rh MICA; TMPY-02053; AAH16929.1; Met1-Gln308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundMHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree of polymorphism. The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules do not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. The Natural killer group 2D (NKG2D), a C-type lectin-like activating immunoreceptor, is a receptor of MICA, which was detected on most gamma-delta T cells, CD8+ alpha-beta T cells, and natural killer (NK) cells. Effector cells from all these subsets could be stimulated by the ligation of NKG2D. Engagement of NKG2D activated cytolytic responses of gamma-delta T cells and NK cells against transfectants and epithelial tumor cells expressing MICA. The MICA system is a novel, avidin-free immunohistochemical detection system that provides a significant increase in sensitivity compared to traditional immunodetection systems.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human MICA Protein (TMPY-02053)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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