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Anti-MICA Antibody (3K607)
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Catalog No. TMAY-02316
Alias PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2
Anti-MICA Antibody (3K607) is a Mouse antibody targeting MICA. Anti-MICA Antibody (3K607) can be used in ELISA,FCM.
Anti-MICA Antibody (3K607)
Anti-MICA Antibody (3K607)
😃Good
Catalog No. TMAY-02316Alias PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2
Anti-MICA Antibody (3K607) is a Mouse antibody targeting MICA. Anti-MICA Antibody (3K607) can be used in ELISA,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Chemical Properties
| Description | Anti-MICA Antibody (3K607) is a Mouse antibody targeting MICA. Anti-MICA Antibody (3K607) can be used in ELISA,FCM. |
| Alias | PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3K607 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human MICA expression on HeLa cells. Cells were stained with purified anti-Human MICA, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | ELISA,FCM |
| Recommended Dose | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICA (rh MICA; TMPY-02053; AAH16929.1; Met1-Gln308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree of polymorphism. The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules do not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. The Natural killer group 2D (NKG2D), a C-type lectin-like activating immunoreceptor, is a receptor of MICA, which was detected on most gamma-delta T cells, CD8+ alpha-beta T cells, and natural killer (NK) cells. Effector cells from all these subsets could be stimulated by the ligation of NKG2D. Engagement of NKG2D activated cytolytic responses of gamma-delta T cells and NK cells against transfectants and epithelial tumor cells expressing MICA. The MICA system is a novel, avidin-free immunohistochemical detection system that provides a significant increase in sensitivity compared to traditional immunodetection systems. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human MICA Protein (TMPY-02053) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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