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Anti-SIGLEC15 Antibody (5U222)
😃Good
Catalog No. TMAB-12793
Anti-SIGLEC15 Antibody (5U222) is a Mouse antibody targeting SIGLEC15. Anti-SIGLEC15 Antibody (5U222) can be used in WB.
Anti-SIGLEC15 Antibody (5U222)
Anti-SIGLEC15 Antibody (5U222)
😃Good
Catalog No. TMAB-12793
Anti-SIGLEC15 Antibody (5U222) is a Mouse antibody targeting SIGLEC15. Anti-SIGLEC15 Antibody (5U222) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,058 | 7-10 days | 7-10 days | |
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SIGLEC15 Antibody (5U222) is a Mouse antibody targeting SIGLEC15. Anti-SIGLEC15 Antibody (5U222) can be used in WB. |
| Clone | 5U222 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Expressed in macrophage and/or dendritic cells of spleen and lymph nodes. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Two families of mammalian lectin-like adhesion molecules, the selectins and the sialoadhesins, bind glycoconjugate ligands in a sialic acid-dependent manner. The sialic acid-binding immunoglobulin superfamily lectins, designated Siglecs or sialoadhesins, recognize sialylated ligands and play a key role in mediating sialic-acid dependent binding to cells. Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. |
| Immunogen | Recombinant Protein: human SIGLEC15 protein |
| Antigen Species | Human |
| Gene Name | SIGLEC15 |
| Gene ID | |
| Protein Name | Sialic acid-binding Ig-like lectin 15 |
| Uniprot ID | |
| Function | Binds sialylated glycoproteins. |
| Molecular Weight | Theoretical: 34 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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