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Anti-CD16B Antibody (6C161)

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Catalog No. TMAB-03878

Anti-CD16B Antibody (6C161) is a antibody targeting CD16B. Anti-CD16B Antibody (6C161) can be used in IHC-P,IHC-Fr,IF.

Anti-CD16B Antibody (6C161)

Anti-CD16B Antibody (6C161)

Copy Product Info
😃Good
Catalog No. TMAB-03878
Anti-CD16B Antibody (6C161) is a antibody targeting CD16B. Anti-CD16B Antibody (6C161) can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD16B Antibody (6C161) is a antibody targeting CD16B. Anti-CD16B Antibody (6C161) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
6C161
Reactivity
Human
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded Human Lung squamous cell carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD16B mAb Monoclonal Antibody, Unconjugated (TMAB-03878) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Human Liver Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD16B mAb Monoclonal Antibody, Unconjugated (TMAB-03878) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Glioblastoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD16B mAb Monoclonal Antibody, Unconjugated (TMAB-03878) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD16B mAb Monoclonal Antibody, Unconjugated (TMAB-03878) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Chronic tonsillitis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD16B mAb Monoclonal Antibody, Unconjugated (TMAB-03878) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Pyogenic appendicitis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD16B mAb Monoclonal Antibody, Unconjugated (TMAB-03878) at 1: 200 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining.
Application
Recommended Dose
IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000
Antibody Type
Monoclonal
Subcellular Localizationmembrane;Lipid-anchor, GPI-anchor;Secreted
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
Antigen Details
Immunogen
Recombinant Protein: human Fc gamma RIIIB / CD16b (NA2) Protein
Antigen Species
Human
Gene Name
FCGR3B
Gene ID
Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-B
Function
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Chemical Properties
Molecular WeightTheoretical: 26 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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