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Anti-DEC-205 Antibody (4V35)
😃Good
Catalog No. TMAY-02827
Alias lymphocyte antigen 75, LY-75, GP200-MR6, DEC-205, CLEC13B, CD205
Anti-DEC-205 Antibody (4V35) is a Mouse antibody targeting DEC-205. Anti-DEC-205 Antibody (4V35) can be used in ELISA.
Anti-DEC-205 Antibody (4V35)
Anti-DEC-205 Antibody (4V35)
😃Good
Catalog No. TMAY-02827Alias lymphocyte antigen 75, LY-75, GP200-MR6, DEC-205, CLEC13B, CD205
Anti-DEC-205 Antibody (4V35) is a Mouse antibody targeting DEC-205. Anti-DEC-205 Antibody (4V35) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-DEC-205 Antibody (4V35) is a Mouse antibody targeting DEC-205. Anti-DEC-205 Antibody (4V35) can be used in ELISA. |
| Alias | lymphocyte antigen 75, LY-75, GP200-MR6, DEC-205, CLEC13B, CD205 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4V35 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LY75 / DEC-205 / CD205 (rh LY75 / DEC-205 / CD205; TMPY-00322; NP_002340.2;Ala32-Gly1664). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s and OV2008), by directing epithelial-to-mesenchymal transition (EMT) associated with reduced capacity for in vivo EOC cell colonization, as similar/identical signaling pathways were reversely regulated, when compared to mesenchymal LY75 knockdown EOC cells. Diseases associated with LY75 include Pneumonic Plague and Adenoiditis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human LY75 / DEC-205 / CD205 Protein (TMPY-00322) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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