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BCP-NC2-C12 is an ionizable cationic lipid employed in the formation of lipid nanoparticles (LNPs) for in vivo mRNA delivery. BCP-NC2-C12 LNPs, utilizing the CRISPR/Cas9 gene knockout method, achieve approximately a 90% reduction in serum PCSK9 protein levels.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | BCP-NC2-C12 is an ionizable cationic lipid employed in the formation of lipid nanoparticles (LNPs) for in vivo mRNA delivery. BCP-NC2-C12 LNPs, utilizing the CRISPR/Cas9 gene knockout method, achieve approximately a 90% reduction in serum PCSK9 protein levels. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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