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LHC-165

Name: LHC-165
Brand: TargetMol
SKU: T15751
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T15751Cas No. 1258595-14-0

LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.

LHC-165

😃Good

Catalog No. T15751Cas No. 1258595-14-0

LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.

Pack Size	Price	Availability
25 mg	$2,870	3-6 months
50 mg	$3,780	3-6 months
100 mg	$5,200	3-6 months

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Product Introduction

Bioactivity

Description

LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.

Chemical Properties

Molecular Weight	603.55
Formula	C₂₉H₃₂F₂N₃O₇P
Cas No.	1258595-14-0
Relative Density.	1.414 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

1M NaOH: 50 mg/mL (82.84 mM), when pH is adjusted to 12 with NaOH. Sonication is recommended.

Solution Preparation Table

1M NaOH

	1mg	5mg	10mg	50mg
1 mM	1.6569 mL	8.2843 mL	16.5686 mL	82.8432 mL
5 mM	0.3314 mL	1.6569 mL	3.3137 mL	16.5686 mL
10 mM	0.1657 mL	0.8284 mL	1.6569 mL	8.2843 mL
20 mM	0.0828 mL	0.4142 mL	0.8284 mL	4.1422 mL
50 mM	0.0331 mL	0.1657 mL	0.3314 mL	1.6569 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc