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Anti-HGFA Antibody (9A829) (Synonyms: RP11-529E1.2, MGC138397, MGC138395, HGFA)

Catalog No. TMAY-00618 Copy Product Info
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Anti-HGFA Antibody (9A829) is a Rabbit antibody targeting HGFA. Anti-HGFA Antibody (9A829) can be used in ELISA.

Anti-HGFA Antibody (9A829)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00618
Synonyms RP11-529E1.2, MGC138397, MGC138395, HGFA

Anti-HGFA Antibody (9A829) is a Rabbit antibody targeting HGFA. Anti-HGFA Antibody (9A829) can be used in ELISA.

Anti-HGFA Antibody
(9A829)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HGFA Antibody (9A829) is a Rabbit antibody targeting HGFA. Anti-HGFA Antibody (9A829) can be used in ELISA.
SynonymsRP11-529E1.2, MGC138397, MGC138395, HGFA
Ig Type
Rabbit IgG
Clone
9A829
Reactivity
Human
Specificity
Human HGF Activator/HGFA
No cross-reactivity in ELISA with
Human KLK11
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human HGFA / HGF Activator (rh HGFA / HGF Activator; TMPY-00821; NP_001519.1; Met 1-Ser 655).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundHGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is cleaved by thrombin or thermolysin through the endoproteolytic process and forms an active heterodimer linked by a disulfide bond. In turn, the active protease can be inhibited by HGFA inhibitors (HAIs) including HAI-1 and HAI-2. Besides, the HGFA zymogen acquires a strong affinity upon activation and thus may ensure the local action in tissue regeneration in the liver, kidney, and skin. It has been reported that activation of HGF is a critical limiting step in the HGF/SF-induced signaling pathway mediated by Met, and accordingly, aberrant expression of HGFA is implicated in tumorigenesis and progression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human HGFA protein (TMPY-00821)
Antigen Species
Human
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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