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Anti-OTUB2 Antibody (4V813)

(Synonyms: OTU2, OTU deubiquitinase, ubiquitin aldehyde binding 2, OTB2, C14orf137) Copy Product Info
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Synonyms: OTU2, OTU deubiquitinase, ubiquitin aldehyde binding 2, OTB2, C14orf137

Catalog No. TMAY-02522 Copy Product Info
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Anti-OTUB2 Antibody (4V813) is a Rabbit antibody targeting OTUB2. Anti-OTUB2 Antibody (4V813) can be used in ELISA,ICC/IF.
Anti-OTUB2 Antibody
(4V813)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-OTUB2 Antibody (4V813) is a Rabbit antibody targeting OTUB2. Anti-OTUB2 Antibody (4V813) can be used in ELISA,ICC/IF.
SynonymsOTU2, OTU deubiquitinase, ubiquitin aldehyde binding 2, OTB2, C14orf137
Ig Type
Rabbit IgG
Clone
4V813
Reactivity
Human
Specificity
Human OTUB2
Application
Recommended Dose
ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human OTUB2 (rh OTUB2; TMPY-02522; Q96DC9-1; Met1-His234).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundOtubain 2 (OTUB2) is a member of DUBs that belong to the ovarian tumour (OTU) superfamily of proteins which consists of a five-stranded β-sheet sandwiched in between a small helical amino-terminal region consisting of α1 and α2, and a large helical region comprised of α3-α10. Like other DUBs, otubain 2 (OTUB2) cleaves proteins precisely at the ubiquitin-protein bond so that ubiquitylation process can be reversed and regulated. Otubain 2 (OTUB2)'s active-site cleft is sterically occluded by a novel loop conformation resulting in an oxyanion hole, which consists uniquely of backbone amides. Furthermore, the residues that orient and stabilize the active-site histidine of otubain 2 (OTUB2) are different from other cysteine proteases. This reorganization of the active-site topology provides a possible explanation for the low turnover and substrate specificity of the otubains.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human OTUB2 Protein (TMPY-02522)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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