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Anti-LY75/CD205 Antibody (7F139)
😃Good
Catalog No. TMAY-00430
Alias Ly-75, LY75, GP200-MR6, DEC-205, CLEC13B, CD205
Anti-LY75/CD205 Antibody (7F139) is a Rabbit antibody targeting LY75/CD205. Anti-LY75/CD205 Antibody (7F139) can be used in WB.
Anti-LY75/CD205 Antibody (7F139)
Anti-LY75/CD205 Antibody (7F139)
😃Good
Catalog No. TMAY-00430Alias Ly-75, LY75, GP200-MR6, DEC-205, CLEC13B, CD205
Anti-LY75/CD205 Antibody (7F139) is a Rabbit antibody targeting LY75/CD205. Anti-LY75/CD205 Antibody (7F139) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-LY75/CD205 Antibody (7F139) is a Rabbit antibody targeting LY75/CD205. Anti-LY75/CD205 Antibody (7F139) can be used in WB. |
| Alias | Ly-75, LY75, GP200-MR6, DEC-205, CLEC13B, CD205 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7F139 |
| Reactivity | Mouse |
| Verified Activity | Anti-S Tag rabbit monoclonal antibody at 1:1000 dilution. -Lane A: S tag-GFERh(C) transfected 293 cell lysate at 1μg -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
| Application | WB |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the Mouse DEC-205 / LY75. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s and OV2008), by directing epithelial-to-mesenchymal transition (EMT) associated with reduced capacity for in vivo EOC cell colonization, as similar/identical signaling pathways were reversely regulated, when compared to mesenchymal LY75 knockdown EOC cells. Diseases associated with LY75 include Pneumonic Plague and Adenoiditis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Mouse DEC-205 / LY75 |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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