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Anti-MICA Antibody-FITC (3K607)
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Catalog No. TMAY-02316F
Alias PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2
Anti-MICA Antibody-FITC (3K607) is a FITC-conjugated Mouse antibody targeting MICA. Anti-MICA Antibody-FITC (3K607) can be used in FCM.
Anti-MICA Antibody-FITC (3K607)
Anti-MICA Antibody-FITC (3K607)
😃Good
Catalog No. TMAY-02316FAlias PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2
Anti-MICA Antibody-FITC (3K607) is a FITC-conjugated Mouse antibody targeting MICA. Anti-MICA Antibody-FITC (3K607) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $81 | 7-10 days | |
| 100 T | $258 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MICA Antibody-FITC (3K607) is a FITC-conjugated Mouse antibody targeting MICA. Anti-MICA Antibody-FITC (3K607) can be used in FCM. |
| Alias | PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3K607 |
| Reactivity | Human |
| Verified Activity | Profile of anti-MICA reactivity on HeLa cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICA (rh MICA; TMPY-02053; AAH16929.1; Met 1-Gln 308) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree of polymorphism. The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules do not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. The Natural killer group 2D (NKG2D), a C-type lectin-like activating immunoreceptor, is a receptor of MICA, which was detected on most gamma-delta T cells, CD8+ alpha-beta T cells, and natural killer (NK) cells. Effector cells from all these subsets could be stimulated by the ligation of NKG2D. Engagement of NKG2D activated cytolytic responses of gamma-delta T cells and NK cells against transfectants and epithelial tumor cells expressing MICA. The MICA system is a novel, avidin-free immunohistochemical detection system that provides a significant increase in sensitivity compared to traditional immunodetection systems. |
| Conjucates | FITC |
| Others Formats | Unconjugated/APC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human MICA protein (TMPY-02053) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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