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Synonyms: HNMT-S2, HNMT-S1, HMT, histamine N-methyltransferase
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $268 | 7-10 days | 7-10 days |
| Description | Anti-HNMT Antibody (7C164) is a Rabbit antibody targeting HNMT. Anti-HNMT Antibody (7C164) can be used in ELISA,IP,WB. |
| Synonyms | HNMT-S2, HNMT-S1, HMT, histamine N-methyltransferase |
| Ig Type | Rabbit IgG |
| Clone | 7C164 |
| Reactivity | Human |
| Specificity | Human HNMT |
| Application | |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IP: 0.5-2 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human HNMT (rh HNMT; TMPY-02340; AAH20677.1; Met1-Ala292). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | HNMT (Histamine N-methyltransferase) is a Protein Coding gene. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT, the major enzyme for the metabolism of histamine in the rat brain, is potently inhibited by 9-amino-1,2,3,4-tetrahydroacridine (tacrine). Methylation is an important pathway in the biotransformation of many drugs, neurotransmitters, and xenobiotic compounds. Histamine N-methyltransferase (HNMT) catalyzes the N tau-methylation of histamine and structurally related compounds. Histamine N-methyltransferase (HNMT) is believed to be the sole pathway for termination of the neurotransmitter action of histamine in the mammalian brain. That highlights the importance of the inclusion of HNMT for genetic testing of individuals presenting with intellectual disability. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human HNMT protein (TMPY-02340) |
| Antigen Species | Human |
| Biology Area | Neurotransmitter Associated Enzymes |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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