Shopping Cart
Remove All
Your shopping cart is currently empty
HDAC-IN-73
😃Good
Catalog No. T88120Cas No. 2323571-16-8
HDAC-IN-73 (compound p-503), an effective HDAC inhibitor, exhibits IC 50 values of 0.17 and 0.49 µM for HDAC1 and HDAC6 respectively. This compound promotes apoptosis and arrests the cell cycle at the G2/M phase. Additionally, HDAC-IN-73 demonstrates anti-tumor activity.
HDAC-IN-73
😃Good
Catalog No. T88120Cas No. 2323571-16-8
HDAC-IN-73 (compound p-503), an effective HDAC inhibitor, exhibits IC 50 values of 0.17 and 0.49 µM for HDAC1 and HDAC6 respectively. This compound promotes apoptosis and arrests the cell cycle at the G2/M phase. Additionally, HDAC-IN-73 demonstrates anti-tumor activity.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $1,970 | 10-14 weeks | 10-14 weeks | |
| 50 mg | $2,580 | 10-14 weeks | 10-14 weeks | |
| 100 mg | $3,400 | 10-14 weeks | 10-14 weeks |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | HDAC-IN-73 (compound p-503), an effective HDAC inhibitor, exhibits IC 50 values of 0.17 and 0.49 µM for HDAC1 and HDAC6 respectively. This compound promotes apoptosis and arrests the cell cycle at the G2/M phase. Additionally, HDAC-IN-73 demonstrates anti-tumor activity. |
| Targets&IC50 | HDAC1:0.17 μM, HDAC6:0.49 μM |
| In vitro | HDAC-IN-73 (compound p-503) at concentrations of 0-2 µM over 24 hours enhances the protein expression of Ac-α-tubulin and Ac-H3 in HCT116 cells [1]. At concentrations of 0.1-0.4 µM, HDAC-IN-73 can induce apoptosis and cause cell cycle arrest at the G2/M phase [1]. |
| In vivo | HDAC-IN-73 administered intraperitoneally at a dosage of 5 mg/kg every two days for 26 days effectively inhibits tumor growth in the HCT116 xenograft model [1]. Animal Model: 6-week-old female nude mice (BALB/c-nu) [1]. Dosage: 5 mg/kg Administration: I.p.; every 2 days for 26 days. Result: Achieved a significant tumor growth inhibition (TGI) of 74.6%. |
| Molecular Weight | 758.18 |
| Formula | C22H24Br2N4O6Se2 |
| Cas No. | 2323571-16-8 |
| Smiles | C(/C(/C(NCC[Se][Se]CCNC(/C(/CC1=CC(Br)=C(O)C=C1)=N/O)=O)=O)=N\O)C2=CC(Br)=C(O)C=C2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy HDAC-IN-73 | purchase HDAC-IN-73 | HDAC-IN-73 cost | order HDAC-IN-73 | HDAC-IN-73 chemical structure | HDAC-IN-73 in vivo | HDAC-IN-73 in vitro | HDAC-IN-73 formula | HDAC-IN-73 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.