Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-HGFA Antibody (4U68)
😃Good
Catalog No. TMAY-00617
Alias RP11-529E1.2, MGC138397, MGC138395, HGFA
Anti-HGFA Antibody (4U68) is a Mouse antibody targeting HGFA. Anti-HGFA Antibody (4U68) can be used in ELISA.
Anti-HGFA Antibody (4U68)
Anti-HGFA Antibody (4U68)
😃Good
Catalog No. TMAY-00617Alias RP11-529E1.2, MGC138397, MGC138395, HGFA
Anti-HGFA Antibody (4U68) is a Mouse antibody targeting HGFA. Anti-HGFA Antibody (4U68) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | RP11-529E1.2, MGC138397, MGC138395, HGFA |
| Ig Type | Mouse IgG2a |
| Clone | 4U68 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HGFA (rhHGFA; TMPY-00821; NP_001519.1; Met 1-Ser 655). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is cleaved by thrombin or thermolysin through the endoproteolytic process and forms an active heterodimer linked by a disulfide bond. In turn, the active protease can be inhibited by HGFA inhibitors (HAIs) including HAI-1 and HAI-2. Besides, the HGFA zymogen acquires a strong affinity upon activation and thus may ensure the local action in tissue regeneration in the liver, kidney, and skin. It has been reported that activation of HGF is a critical limiting step in the HGF/SF-induced signaling pathway mediated by Met, and accordingly, aberrant expression of HGFA is implicated in tumorigenesis and progression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human HGFA protein (TMPY-00821) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-HGFA Antibody (4U68) | purchase Anti-HGFA Antibody (4U68) | Anti-HGFA Antibody (4U68) cost | order Anti-HGFA Antibody (4U68)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.