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Anti-CD93/C1qR1 Antibody (8N985)
😃Good
Catalog No. TMAY-02387
Alias Ly68, CD93 molecule, C1qrp, C1qr1, AW555904, AA4.1, AA145088, 6030404G09Rik
Anti-CD93/C1qR1 Antibody (8N985) is a Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (8N985) can be used in FCM.
Anti-CD93/C1qR1 Antibody (8N985)
Anti-CD93/C1qR1 Antibody (8N985)
😃Good
Catalog No. TMAY-02387Alias Ly68, CD93 molecule, C1qrp, C1qr1, AW555904, AA4.1, AA145088, 6030404G09Rik
Anti-CD93/C1qR1 Antibody (8N985) is a Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (8N985) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Chemical Properties
| Description | Anti-CD93/C1qR1 Antibody (8N985) is a Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (8N985) can be used in FCM. |
| Alias | Ly68, CD93 molecule, C1qrp, C1qr1, AW555904, AA4.1, AA145088, 6030404G09Rik |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 8N985 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD93 expression on human whole blood monocytes. Cells were stained with purified anti-Human CD93, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD93 / C1qR (rh CD93 / C1qR; TMPY-02268; Q9NPY3; Met1-Lys580). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD93 / C1qR Protein (TMPY-02268) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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