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SC-10

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Catalog No. T23329Cas No. 102649-79-6
Alias SC10

SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.

SC-10

SC-10

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Purity: 99.58%
Catalog No. T23329Alias SC10Cas No. 102649-79-6
SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$41In StockIn Stock
5 mg$96In StockIn Stock
10 mg$156In StockIn Stock
25 mg$313In StockIn Stock
50 mg$496In StockIn Stock
100 mg$787In StockIn Stock
200 mg$1,070In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.58%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.
In vitro
SC-10 (10.001-100μM) treatment of U937 and HL-60 cells failed to induce changes in PKC content in membrane and cytoplasmic fractions, respectively; SC-10 showed a protective effect in HL-60 cells treated with Ara-C; SC-10 showed a modest biological effect on leukemic blasts and could not enhance the apoptotic response of these cells to cytotoxic drugs.[1]
SynonymsSC10
Chemical Properties
Molecular Weight339.88
FormulaC17H22ClNO2S
Cas No.102649-79-6
SmilesO=S(=O)(NCCCCCCC)C=1C=CC=C2C(Cl)=CC=CC21
Relative Density.1.192g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2 mg/mL (5.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9422 mL14.7111 mL29.4221 mL147.1107 mL
5 mM0.5884 mL2.9422 mL5.8844 mL29.4221 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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