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Anti-CD209/DC-SIGN Antibody (8Q432) (Synonyms: MGC129965, DC-SIGN1, DC-SIGN, CLEC4L, CDSIGN, CD209 molecule...)

Name: Anti-CD209/DC-SIGN Antibody (8Q432)
Brand: TargetMol
SKU: TMAY-00445
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00445 Copy Product Info

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Anti-CD209/DC-SIGN Antibody (8Q432) is a Mouse antibody targeting CD209/DC-SIGN. Anti-CD209/DC-SIGN Antibody (8Q432) can be used in ELISA(Cap),FCM.

Anti-CD209/DC-SIGN Antibody (8Q432)

Copy Product Info

🥰Excellent

Catalog No. TMAY-00445

Synonyms MGC129965, DC-SIGN1, DC-SIGN, CLEC4L, CDSIGN, CD209 molecule, CD209

Anti-CD209/DC-SIGN Antibody (8Q432) is a Mouse antibody targeting CD209/DC-SIGN. Anti-CD209/DC-SIGN Antibody (8Q432) can be used in ELISA(Cap),FCM.

Anti-CD209/DC-SIGN Antibody
(8Q432)

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$69	7-10 days	7-10 days
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-CD209/DC-SIGN Antibody (8Q432) is a Mouse antibody targeting CD209/DC-SIGN. Anti-CD209/DC-SIGN Antibody (8Q432) can be used in ELISA(Cap),FCM.
Synonyms	MGC129965, DC-SIGN1, DC-SIGN, CLEC4L, CDSIGN, CD209 molecule, CD209
Ig Type	Mouse IgG1
Clone	8Q432
Reactivity	Human
Specificity	Human DC-SIGN/CD209
Verified Activity	Flow cytometric analysis of Human CD209 expression on DC. Cells were stained with purified anti-Human CD209, then a PE-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	ELISA(Cap) FCM
Recommended Dose	FCM: 1:25-1:100; ELISA(Cap): 1:250-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD209 / DC-SIGN. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable of binding ICAM-3 on resting T cells in the secondary lymphoid organs, providing the initial contact between these cells during the establishment of cell-mediated immunity. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. It has an important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors. DC-SIGN also mediates the capture and internalization of viral, bacterial, and fungal pathogens by dendritic cells, such as HIV-1, Ebola virus, cytomegalovirus, Dengue virus, and hepatitis C virus. DC-SIGN is unique in that it regulates adhesion processes, such as DC trafficking and T-cell synapse formation, as well as antigen capture. Moreover, even though several C-type lectins have been shown to bind HIV-1, DC-SIGN does not only capture HIV-1 but also protects it in early endosomes allowing HIV-1 transport by DC to lymphoid tissues, where it enhances trans infection of T cells.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	APC/FITC/PE
Antibody Types Available	4

Antigen Details

Immunogen	Recombinant Protein: Human CD209 / DC-SIGN Protein (Cat# 10200-H01H)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

MGC-129965MGC 129965CD-209CD 209

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