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HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.

Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.

Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.

Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.

Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium (Cefotaxim sodium salt) is marketed under various trade names including Claforan (Sanofi-Aventis).

Cefpirome sulfate (HR-810 sulfate) is a fourth-generation cephalosporin antibiotic.

Cefotaxime is an inhibitor of penicillin binding protein.

Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin IgM and IgG secretion in vitro and in vivo, with an IC50=2.5 μm, and exerts an immunosuppressive effect by interfering with pyrimidine metabolism, and is used in the study of neuralgia.

Fonsartan is an angiotensin receptor antagonist. Fonsartan inhibits the angiotensin II-induced trophic effects, fibronectin release and fibronectin-EIIIA+ expression in rat aortic vascular smooth muscle cells in vitro.

Cefpirome is a broad-spectrum, fourth-generation cephalosporin. It binds to and inactivates penicillin-binding proteins located on the inner membrane of the bacterial cell wall.

HR-568 displays broad-spectrum anti-enterovirus activity. It inhibits enterovirus strains EV-A71, E30, and CVA24 in MRC-5 cells, with EC50 values of 1.53 μM, 0.4 μM, and 1.22 μM, respectively. HR-568 targets the hydrophobic pocket on enterovirus capsid proteins, thereby hindering viral replication.

HR-19011 (Compound 40) is an inducer of eIF2α phosphorylation that increases expression levels of downstream proteins ATF and CHOP, exhibiting micromolar-level antiproliferative activity against K562 and PBMC cells.

Tepirindole (also known as HR-592) is an indole derivative that exhibits high affinity for DA, 5-HT, and NE receptors, yet it possesses minimal ability to induce rigidity.

HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.

HR488B is a potent inhibitor of HDAC1. It specifically hinders the growth of CRC cells by inducing cell cycle arrest at the G0/G1 phase and promoting apoptosis. Furthermore, HR488B leads to mitochondrial dysfunction, the production of reactive oxygen species (ROS), and the accumulation of DNA damage.

HR2-18 is a bioactive peptide that inhibits SARS-CoV penetration into cells.

HR1, a mastoid protease, enhances the permeability of human erythrocyte membranes and can induce cytoplasmic membrane permeation in bacteria and mast cells [1].

HR68, a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid, serves as an anticancer agent. It effectively reduces the viability of LN-229 glioblastoma cells, with an IC50 value of 1.17 µM. Notably, HR68 is capable of crossing the blood-brain barrier in temozolomide-resistant orthotopic patient-derived xenograft (PDX) mouse models of glioblastoma.

HR97 TFA is a cell-penetrating peptide that binds with engineered melanin to produce the eye drop solution HR97-SunitiGel. The peptide-drug conjugate within HR97-SunitiGel allows for sustained ocular drug delivery.

Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor.

Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.

Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.

HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.

AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.