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Synonyms: P450DX, P450-C, P1-450, CYP1, CP11, AHRR, AHH
Anti-CYP1A1 Monoclonal Antibody
(5U626)

| Description | Anti-CYP1A1 Monoclonal Antibody (5U626) is a Mouse antibody targeting CYP1A1. Anti-CYP1A1 Monoclonal Antibody (5U626) can be used in IHC. |
| Synonyms | P450DX, P450-C, P1-450, CYP1, CP11, AHRR, AHH |
| Ig Type | IgG1 |
| Clone | 5U626 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CYP1A1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CYP1A1 |
| Gene ID | |
| Protein Name | Cytochrome P450 1A1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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