(Rac)-VU 6008667

Name: (Rac)-VU 6008667
Brand: TargetMol
SKU: T12679
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12679Cas No. 2092917-63-8

(Rac)-VU 6008667 is a selective negative allosteric modulator of the muscarinic acetylcholine receptor subtype 5 (M5 NAM), with an IC50 of 1.8 μM and a pIC50 of 5.75, exhibiting high CNS penetration.

(Rac)-VU 6008667

🥰Excellent

Purity: 99.82%

Catalog No. T12679Cas No. 2092917-63-8

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$34	-	In Stock
5 mg	$62	-	In Stock
10 mg	$113	-	In Stock
25 mg	$193	-	In Stock
50 mg	$283	-	In Stock
100 mg	$423	-	In Stock
200 mg	$589	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.82%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	(Rac)-VU 6008667 is a selective negative allosteric modulator of the muscarinic acetylcholine receptor subtype 5 (M5 NAM), with an IC50 of 1.8 μM and a pIC50 of 5.75, exhibiting high CNS penetration.
Targets&IC50	M5:1.8 μM, M5:1.8 μM

Chemical Properties

Molecular Weight	438.85
Formula	C₂₄H₁₇ClF₂N₂O₂
Cas No.	2092917-63-8
Smiles	C(=O)(N1C2(C=3C(C(=O)N2CC1)=CC=CC3)C4=CC(C)=C(Cl)C=C4)C5=CC(F)=C(F)C=C5
Relative Density.	1.48 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: 20 mg/mL (45.57 mM), Sonication is recommended. H2O: 0.1 mg/mL (0.23 mM)

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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