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Anti-Thrombomodulin Antibody (3U828) is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (3U828) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-Thrombomodulin Antibody (3U828) is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (3U828) can be used in ELISA. |
Alias | TM, thrombomodulin, THRM, THPH12, CD141, BDCA3, AHUS6 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 3U828 |
Reactivity | Rat |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat Thrombomodulin / THBD (TMPY-03271; O35370; Met1-Ser517). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Thrombomodulin, also known as THBD (CD141), is an integral membrane protein that reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome. |
Conjucates | Unconjugated |
Immunogen | Recombinant Rat Thrombomodulin / THBD protein (TMPY-03271) |
Antigen Species | Rat |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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