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Anti-Thrombomodulin Antibody (3U828) is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (3U828) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $268 | 7-10 days | 7-10 days |
| Description | Anti-Thrombomodulin Antibody (3U828) is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (3U828) can be used in ELISA. |
| Synonyms | TM, thrombomodulin, THRM, THPH12, CD141, BDCA3, AHUS6 |
| Ig Type | Rabbit IgG |
| Clone | 3U828 |
| Reactivity | Rat |
| Specificity | Rat Thrombomodulin |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat Thrombomodulin / THBD (TMPY-03271; O35370; Met1-Ser517). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Thrombomodulin, also known as THBD (CD141), is an integral membrane protein that reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat Thrombomodulin / THBD protein (TMPY-03271) |
| Antigen Species | Rat |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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