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Anti-Thrombomodulin Antibody (3U828) is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (3U828) can be used in ELISA.
| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 100 μL | $268 | 7-10 days | 
| Description | Anti-Thrombomodulin Antibody (3U828) is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (3U828) can be used in ELISA. | 
| Synonyms | TM, thrombomodulin, THRM, THPH12, CD141, BDCA3, AHUS6 | 
| Ig Type | Rabbit IgG | 
| Clone | 3U828 | 
| Reactivity | Rat | 
| Specificity | Rat Thrombomodulin | 
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 | 
| Antibody Type | Monoclonal | 
| Host Species | Rabbit | 
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat Thrombomodulin / THBD (TMPY-03271; O35370; Met1-Ser517). | 
| Purification | Protein A | 
| Appearance | Liquid | 
| Formulation | 0.2 μm filtered solution in PBS | 
| Research Background | Thrombomodulin, also known as THBD (CD141), is an integral membrane protein that reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome. | 
| Conjucates | Unconjugated | 
| Immunogen | Recombinant Protein: Rat Thrombomodulin / THBD protein (TMPY-03271) | 
| Antigen Species | Rat | 
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. | 
| Transport | Shipping with blue ice. | 

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