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Synonyms: WNCHRS, MTMMP1, MT-MMP 1, MT-MMP, MT1-MMP, MT1MMP, MMP-X1, MMP-14
Anti-MMP14 Monoclonal Antibody
(9F476)

| Description | Anti-MMP14 Monoclonal Antibody (9F476) is a Mouse antibody targeting MMP14. Anti-MMP14 Monoclonal Antibody (9F476) can be used in IHC,FCM. |
| Synonyms | WNCHRS, MTMMP1, MT-MMP 1, MT-MMP, MT1-MMP, MT1MMP, MMP-X1, MMP-14 |
| Ig Type | IgG1 |
| Clone | 9F476 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human MMP14 (AA: 112-246) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | MMP14 |
| Gene ID | |
| Protein Name | Matrix metalloproteinase-14 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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