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Anti-MMP14 Monoclonal Antibody (9F476)

(Synonyms: WNCHRS, MTMMP1, MT-MMP 1, MT-MMP, MT1-MMP, MT1MMP, MMP-X1, MMP-14) Copy Product Info
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Synonyms: WNCHRS, MTMMP1, MT-MMP 1, MT-MMP, MT1-MMP, MT1MMP, MMP-X1, MMP-14

Catalog No. TMAT-1085 Copy Product Info
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Anti-MMP14 Monoclonal Antibody (9F476) is a Mouse antibody targeting MMP14. Anti-MMP14 Monoclonal Antibody (9F476) can be used in IHC,FCM.

Anti-MMP14 Monoclonal Antibody
(9F476)

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Product Introduction

Bioactivity
Description
Anti-MMP14 Monoclonal Antibody (9F476) is a Mouse antibody targeting MMP14. Anti-MMP14 Monoclonal Antibody (9F476) can be used in IHC,FCM.
SynonymsWNCHRS, MTMMP1, MT-MMP 1, MT-MMP, MT1-MMP, MT1MMP, MMP-X1, MMP-14
Ig Type
IgG1
Clone
9F476
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human MMP14 (AA: 112-246) expressed in E. Coli.
Antigen Species
Human
Gene Name
MMP14
Gene ID
Protein Name
Matrix metalloproteinase-14
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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