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Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell entry by competing with membrane-bound ACE2, offering potential in the research of SARS-CoV-2 [1] [2].
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Description | Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell entry by competing with membrane-bound ACE2, offering potential in the research of SARS-CoV-2 [1] [2]. |
In vitro | Alunacedase alfa exhibits high-affinity binding to the SARS-CoV-2 spike glycoprotein, with an estimated affinity of roughly 1.2 nM [2]. |
Synonyms | HrsACE2, GSK 2586881 |
Molecular Weight | N/A |
CAS No. | 2416824-55-8 |
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Alunacedase alfa 2416824-55-8 Microbiology/Virology SARS-CoV HrsACE2 GSK 2586881 inhibitor inhibit