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Alunacedase alfa

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Catalog No. T80587Cas No. 2416824-55-8
Alias HrsACE2, GSK2586881, GSK 2586881, APN-01, APN 01

Alunacedase alfa (APN-01) is a soluble angiotensin-converting enzyme 2 (hrsACE2) with antiviral activity that reduces the competitive entry of SARS-CoV-2 into cell membranes bound to ACE2. alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury. Alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury.

Alunacedase alfa

Alunacedase alfa

Copy Product Info
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Catalog No. T80587Alias HrsACE2, GSK2586881, GSK 2586881, APN-01, APN 01Cas No. 2416824-55-8
Alunacedase alfa (APN-01) is a soluble angiotensin-converting enzyme 2 (hrsACE2) with antiviral activity that reduces the competitive entry of SARS-CoV-2 into cell membranes bound to ACE2. alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury. Alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$248-In Stock
5 mg$625-In Stock
10 mg$889-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.1% (SDS-PAGE); 99.9% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Alunacedase alfa (APN-01) is a soluble angiotensin-converting enzyme 2 (hrsACE2) with antiviral activity that reduces the competitive entry of SARS-CoV-2 into cell membranes bound to ACE2. alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury. Alunacedase alfa mimics ACE2 in vivo and can be used to study novel coronavirus infections, pulmonary hypertension and acute lung injury.
Targets&IC50
SARS-CoV-2 spike glycoprotein:1.2 nM (Kd)
In vitro
Alunacedase alfa exhibits high-affinity binding to the SARS-CoV-2 spike glycoprotein, with an estimated affinity of roughly 1.2 nM. [2]
SynonymsHrsACE2, GSK2586881, GSK 2586881, APN-01, APN 01
Reactivity
Virus
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetAngiotensinII
Chemical Properties
Molecular Weight85.03 kDa
Cas No.2416824-55-8
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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