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Anti-RAD50 Monoclonal Antibody (8N286)
(Synonyms: RAD502, NBSLD, hRad50) Copy Product Info
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Synonyms: RAD502, NBSLD, hRad50
Catalog No. TMAT-1463 Copy Product Info
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Anti-RAD50 Monoclonal Antibody (8N286) is a Mouse antibody targeting RAD50. Anti-RAD50 Monoclonal Antibody (8N286) can be used in WB,IHC,FCM.
Anti-RAD50 Monoclonal Antibody
(8N286)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-RAD50 Monoclonal Antibody (8N286) is a Mouse antibody targeting RAD50. Anti-RAD50 Monoclonal Antibody (8N286) can be used in WB,IHC,FCM. |
| Synonyms | RAD502, NBSLD, hRad50 |
| Ig Type | IgG2a |
| Clone | 8N286 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human RAD50 (AA: 228-359) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RAD50 |
| Gene ID | |
| Protein Name | DNA repair protein RAD50 |
| Uniprot ID |
| Molecular Weight | Theoretical: 154 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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