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Tribendimidine

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Catalog No. T62769Cas No. 115103-15-6

Tribendimidine is a broad-spectrum, orally active anthelmintic and an L-type nicotinic acetylcholine receptor (nAChR) agonist. tribendimidine is highly active against A. lumbricoides and N. americanus.

Tribendimidine

Tribendimidine

😃Good
Catalog No. T62769Cas No. 115103-15-6
Tribendimidine is a broad-spectrum, orally active anthelmintic and an L-type nicotinic acetylcholine receptor (nAChR) agonist. tribendimidine is highly active against A. lumbricoides and N. americanus.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$48In StockIn Stock
10 mg$82In StockIn Stock
25 mg$166In StockIn Stock
50 mg$249In StockIn Stock
100 mg$374-In Stock
1 mL x 10 mM (in DMSO)$82In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:≥98%
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COA HNMR

Product Introduction

Bioactivity
Description
Tribendimidine is a broad-spectrum, orally active anthelmintic and an L-type nicotinic acetylcholine receptor (nAChR) agonist. tribendimidine is highly active against A. lumbricoides and N. americanus.
Chemical Properties
Molecular Weight452.59
FormulaC28H32N6
Cas No.115103-15-6
SmilesCN(C)C(\C)=N\c1ccc(cc1)\N=C\c1ccc(\C=N\c2ccc(cc2)\N=C(/C)N(C)C)cc1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (99.43 mM), when pH is adjusted to 3 with HCl. Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.42 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2095 mL11.0475 mL22.0951 mL110.4753 mL
5 mM0.4419 mL2.2095 mL4.4190 mL22.0951 mL
10 mM0.2210 mL1.1048 mL2.2095 mL11.0475 mL
20 mM0.1105 mL0.5524 mL1.1048 mL5.5238 mL
50 mM0.0442 mL0.2210 mL0.4419 mL2.2095 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

nAChR
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