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Anti-UHRF1 Monoclonal Antibody (1M530)
(Synonyms: TDRD22, RNF106, Np95, ICBP90, huNp95, hUHRF1, hNP95) Copy Product Info
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Synonyms: TDRD22, RNF106, Np95, ICBP90, huNp95, hUHRF1, hNP95
Catalog No. TMAT-1498 Copy Product Info
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Anti-UHRF1 Monoclonal Antibody (1M530) is a Mouse antibody targeting UHRF1. Anti-UHRF1 Monoclonal Antibody (1M530) can be used in WB,IHC,IF,FCM.
Anti-UHRF1 Monoclonal Antibody
(1M530)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-UHRF1 Monoclonal Antibody (1M530) is a Mouse antibody targeting UHRF1. Anti-UHRF1 Monoclonal Antibody (1M530) can be used in WB,IHC,IF,FCM. |
| Synonyms | TDRD22, RNF106, Np95, ICBP90, huNp95, hUHRF1, hNP95 |
| Ig Type | IgG2b |
| Clone | 1M530 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human UHRF1 (AA: 616-755) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | UHRF1 |
| Gene ID | |
| Protein Name | E3 ubiquitin-protein ligase UHRF1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 89.8 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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