Shopping Cart
Remove All
Your shopping cart is currently empty
K1-70
😃Good
Catalog No. T77360
Alias Anti-TSHR Antibody (K1-70)
K1-70 is a humanized antibody targeting TSHR, used in the study of autoimmune diseases and endocrine disorders.
K1-70
K1-70
😃Good
Catalog No. T77360Alias Anti-TSHR Antibody (K1-70)
K1-70 is a humanized antibody targeting TSHR, used in the study of autoimmune diseases and endocrine disorders.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $125 | - | In Stock | |
| 5 mg | $398 | - | In Stock | |
| 10 mg | $639 | - | In Stock | |
| 25 mg | $1,086 | - | In Stock | |
| 50 mg | $1,629 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:>95.0% (SDS-PAGE); 98.09% (SEC-HPLC)
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | K1-70 is a humanized antibody targeting TSHR, used in the study of autoimmune diseases and endocrine disorders. |
| Targets&IC50 | TSHR (human):851.2 ng/mL (EC50) |
| In vitro | K1-70 is the most potent inhibitor of TSH binding to the receptor, producing 97% inhibition as low as 0.1 μg/mL. [1] K1-70 (0.1 μg/ ml-0.5 μg/mL) inhibited the cyclic AMP stimulating activity of M22 IgG (3 ng/mL) in a dose-dependent manner in CHO cells expressing TSHR. [2] |
| In vivo | K1-70 (100-200 μg) caused serum total and free T4 to decrease to the low levels observed in T3 inhibited rats. [1] |
| Synonyms | Anti-TSHR Antibody (K1-70) |
| Clone | K1-70 |
| Reactivity | Human |
| Verified Activity | Immobilized TSHR-VLP at 2 μg/mL can bind K1-70. The EC50 is 0.8512 μg/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TSHR/LGR3 |
| Molecular Weight | 143.54 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 lambda |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy K1-70 | purchase K1-70 | K1-70 cost | order K1-70 | K1-70 in vivo | K1-70 in vitro | K1-70 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.