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Anti-EphB2 Antibody
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Catalog No. T9901A-1274
Anti-EphB2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human ephrin type-B receptor 2 (EphB2) with exceptional binding affinity. It effectively facilitates the measurable blockade of EphB2-mediated forward signaling across various preclinical experimental models to evaluate the disruption of tumor cell migration and invasiveness during strictly monitored laboratory observation periods and functional cell survival assays.
Anti-EphB2 Antibody
Anti-EphB2 Antibody
Copy Product Info🥰Excellent
Catalog No. T9901A-1274
Anti-EphB2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human ephrin type-B receptor 2 (EphB2) with exceptional binding affinity. It effectively facilitates the measurable blockade of EphB2-mediated forward signaling across various preclinical experimental models to evaluate the disruption of tumor cell migration and invasiveness during strictly monitored laboratory observation periods and functional cell survival assays.
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| Description | Anti-EphB2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human ephrin type-B receptor 2 (EphB2) with exceptional binding affinity. It effectively facilitates the measurable blockade of EphB2-mediated forward signaling across various preclinical experimental models to evaluate the disruption of tumor cell migration and invasiveness during strictly monitored laboratory observation periods and functional cell survival assays. |
| Targets&IC50 | EphB2:< 1 nM(Kd) |
| In vitro | In human cancer cell lines expressing EphB2, Anti-EphB2 Antibody conjugates induced rapid internalization and potent cell killing with IC50 in the nanomolar range [1]. |
| In vivo | In human colorectal cancer xenograft models, systemic administration of Anti-EphB2 Antibody conjugates significantly inhibited tumor growth [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | EphB2 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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