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Anti-EphB2 Antibody

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Catalog No. T9901A-1274 Copy Product Info
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Anti-EphB2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human ephrin type-B receptor 2 (EphB2) with exceptional binding affinity. It effectively facilitates the measurable blockade of EphB2-mediated forward signaling across various preclinical experimental models to evaluate the disruption of tumor cell migration and invasiveness during strictly monitored laboratory observation periods and functional cell survival assays.
Anti-EphB2 Antibody
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$238InquiryInquiry
5 mg$718InquiryInquiry
10 mg$1,150InquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-EphB2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human ephrin type-B receptor 2 (EphB2) with exceptional binding affinity. It effectively facilitates the measurable blockade of EphB2-mediated forward signaling across various preclinical experimental models to evaluate the disruption of tumor cell migration and invasiveness during strictly monitored laboratory observation periods and functional cell survival assays.
Targets & IC50
EphB2:< 1 nM(Kd)
In vitro
In human cancer cell lines expressing EphB2, Anti-EphB2 Antibody conjugates induced rapid internalization and potent cell killing with IC50 in the nanomolar range [1].
In vivo
In human colorectal cancer xenograft models, systemic administration of Anti-EphB2 Antibody conjugates significantly inhibited tumor growth [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetEphB2
Antibody Information
IsotypeIgG1
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-EphB2 Antibody chemical structure | Anti-EphB2 Antibody in vivo | Anti-EphB2 Antibody in vitro