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3-Bromocytisine

Name: 3-Bromocytisine
Brand: TargetMol
SKU: T10108
Price: 92 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10108Cas No. 207390-14-5

Alias 3-Br-cytisine, (-)-9-Bromocytisine, (-)-3-Bromocytisine

3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).

3-Bromocytisine

🥰Excellent

Purity: 99.974%

Catalog No. T10108Alias 3-Br-cytisine, (-)-9-Bromocytisine, (-)-3-BromocytisineCas No. 207390-14-5

3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$92	In Stock	In Stock
5 mg	$225	In Stock	In Stock
10 mg	$325	In Stock	In Stock
25 mg	$548	In Stock	In Stock
50 mg	$788	In Stock	In Stock
100 mg	$1,080	In Stock	In Stock
200 mg	$1,450	-	In Stock
1 mL x 10 mM (in DMSO)	$198	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.974%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).
Targets&IC50	α7 (human):31.6 nM , α4β4 (human):0.28 nM , α4β2 (human):0.30 nM
In vitro	3-Bromocytisine shows different effects on high and low ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively [2].
Synonyms	3-Br-cytisine, (-)-9-Bromocytisine, (-)-3-Bromocytisine

Chemical Properties

Molecular Weight	269.14
Formula	C₁₁H₁₃BrN₂O
Cas No.	207390-14-5
Smiles	O=C1N2C([C@@]3(C[C@](C2)(CNC3)[H])[H])=CC=C1Br
Relative Density.	1.61 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (185.78 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.43 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7155 mL	18.5777 mL	37.1554 mL	185.7769 mL
5 mM	0.7431 mL	3.7155 mL	7.4311 mL	37.1554 mL
10 mM	0.3716 mL	1.8578 mL	3.7155 mL	18.5777 mL
20 mM	0.1858 mL	0.9289 mL	1.8578 mL	9.2888 mL
50 mM	0.0743 mL	0.3716 mL	0.7431 mL	3.7155 mL
100 mM	0.0372 mL	0.1858 mL	0.3716 mL	1.8578 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc