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Anti-CHRNA4 Monoclonal Antibody (1R161)

(Synonyms: NACRA4, NACHRA4, NACHR, EBN1, EBN, BFNC) Copy Product Info
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Synonyms: NACRA4, NACHRA4, NACHR, EBN1, EBN, BFNC

Catalog No. TMAT-1052 Copy Product Info
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Anti-CHRNA4 Monoclonal Antibody (1R161) is a Mouse antibody targeting CHRNA4. Anti-CHRNA4 Monoclonal Antibody (1R161) can be used in FCM.

Anti-CHRNA4 Monoclonal Antibody
(1R161)

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Product Introduction

Bioactivity
Description
Anti-CHRNA4 Monoclonal Antibody (1R161) is a Mouse antibody targeting CHRNA4. Anti-CHRNA4 Monoclonal Antibody (1R161) can be used in FCM.
SynonymsNACRA4, NACHRA4, NACHR, EBN1, EBN, BFNC
Ig Type
IgG1
Clone
1R161
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CHRNA4 (AA: extra 29-242) expressed in E. Coli.
Antigen Species
Human
Gene Name
CHRNA4
Gene ID
Protein Name
Neuronal acetylcholine receptor subunit alpha-4
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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