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Synonyms: NACRA4, NACHRA4, NACHR, EBN1, EBN, BFNC
Anti-CHRNA4 Monoclonal Antibody
(1R161)

| Description | Anti-CHRNA4 Monoclonal Antibody (1R161) is a Mouse antibody targeting CHRNA4. Anti-CHRNA4 Monoclonal Antibody (1R161) can be used in FCM. |
| Synonyms | NACRA4, NACHRA4, NACHR, EBN1, EBN, BFNC |
| Ig Type | IgG1 |
| Clone | 1R161 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CHRNA4 (AA: extra 29-242) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CHRNA4 |
| Gene ID | |
| Protein Name | Neuronal acetylcholine receptor subunit alpha-4 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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