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UB 165 fumarate

Name: UB 165 fumarate
Brand: TargetMol
SKU: T13241
Rating: 4.5 (1 reviews)

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Catalog No. T13241Cas No. 2454492-43-2

Alias UB-165 fumarate, UB165 fumarate

UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding to [3H]-nicotine measured in rat brain.

UB 165 fumarate

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Purity: 99.72%

Catalog No. T13241Alias UB-165 fumarate, UB165 fumarateCas No. 2454492-43-2

Pack Size	Price	Availability
1 mg	$350	6-8 weeks
25 mg	$1,520	6-8 weeks
50 mg	$1,980	6-8 weeks
100 mg	$2,500	6-8 weeks

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.72%

ee:100%

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Product Introduction

Bioactivity

Description	UB 165 fumarate is an agonist of the nAChR, a partial agonist of the α4β2 subtype, and a full agonist of the α3β2 subtype, with a Ki value of 0.27 nM for binding to [3H]-nicotine measured in rat brain.
Targets&IC50	Nicotine (rat brain):ki:0.27 nM , Nicotine (rat brain):0.27 nM(ki)
In vitro	UB-165 fumarate exhibits an EC50 value of 88 nM for stimulating [3H]-dopamine release from striatal synaptosomes.[1]
Synonyms	UB-165 fumarate, UB165 fumarate

Chemical Properties

Molecular Weight	350.8
Formula	C₁₇H₁₉ClN₂O₄
Cas No.	2454492-43-2
Smiles	C(=C/C(O)=O)\C(O)=O.ClC=1C=CC(C=2[C@@]3(N[C@@](CC3)(CCC2)[H])[H])=CN1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

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