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Anti-NRG3 Antibody (8U198) is a Mouse antibody targeting NRG3. Anti-NRG3 Antibody (8U198) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-NRG3 Antibody (8U198) is a Mouse antibody targeting NRG3. Anti-NRG3 Antibody (8U198) can be used in ELISA. |
Alias | pro-NRG3, neuregulin 3, HRG3 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 8U198 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NRG-3 / Neuregulin-3 (rh NRG-3 / Neuregulin-3; TMPY-04300; ADK90021.1; Glu282-Pro342). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signaling through ERBB4. NRG3, a brain-enriched neurotrophin, undergoes alternative splicing and is implicated in several neurological disorders with developmental origins. It also promotes mammary differentiation during embryogenesis. NRG3 promotes early mammary morphogenesis and acts during specification of the mammary placode, an aggregate of epithelial cells that form during mid-embryogenesis. Diseases associated with NRG3 include Schizophrenia and Schizoaffective Disorder. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human NRG-3 / Neuregulin-3 Protein (TMPY-04300) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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