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Tinoridine

Name: Tinoridine
Brand: TargetMol
SKU: T50001
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T50001Cas No. 24237-54-5

Alias ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate

Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2). It has anti-inflammatory, anti-allergic and anticoagulant activities.

Tinoridine

🥰Excellent

Purity: 99.08%

Catalog No. T50001Alias ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylateCas No. 24237-54-5

Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2). It has anti-inflammatory, anti-allergic and anticoagulant activities.

Pack Size	Price	Availability
50 mg	$41	In Stock
100 mg	$62	In Stock
200 mg	$92	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.08%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2). It has anti-inflammatory, anti-allergic and anticoagulant activities.
Targets&IC50	CYP2D6 (human):0.0098µM
Synonyms	ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate

Chemical Properties

Molecular Weight	316.42
Formula	C₁₇H₂₀N₂O₂S
Cas No.	24237-54-5
Smiles	CCOC(=O)c1c(N)sc2CN(Cc3ccccc3)CCc12
Relative Density.	1.256 g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (158.02 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1604 mL	15.8018 mL	31.6036 mL	158.0178 mL
5 mM	0.6321 mL	3.1604 mL	6.3207 mL	31.6036 mL
10 mM	0.3160 mL	1.5802 mL	3.1604 mL	15.8018 mL
20 mM	0.1580 mL	0.7901 mL	1.5802 mL	7.9009 mL
50 mM	0.0632 mL	0.3160 mL	0.6321 mL	3.1604 mL
100 mM	0.0316 mL	0.1580 mL	0.3160 mL	1.5802 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc