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Anti-CHRNA2 Monoclonal Antibody (9T477)
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Catalog No. TMAT-1348 Copy Product Info
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Anti-CHRNA2 Monoclonal Antibody (9T477) is a Mouse antibody targeting CHRNA2. Anti-CHRNA2 Monoclonal Antibody (9T477) can be used in WB.
Anti-CHRNA2 Monoclonal Antibody
(9T477)
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| Description | Anti-CHRNA2 Monoclonal Antibody (9T477) is a Mouse antibody targeting CHRNA2. Anti-CHRNA2 Monoclonal Antibody (9T477) can be used in WB. |
| Ig Type | IgG1 |
| Clone | 9T477 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CHRNA2 (AA: extra 27-264) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CHRNA2 |
| Gene ID | |
| Protein Name | Neuronal acetylcholine receptor subunit alpha-2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 60 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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