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Anti-GHR/Growth Hormone R Antibody (1X157)
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Catalog No. TMAY-03056
Alias growth hormone receptor
Anti-GHR/Growth Hormone R Antibody (1X157) is a Rabbit antibody targeting GHR/Growth Hormone R. Anti-GHR/Growth Hormone R Antibody (1X157) can be used in ELISA.
Anti-GHR/Growth Hormone R Antibody (1X157)
Anti-GHR/Growth Hormone R Antibody (1X157)
😃Good
Catalog No. TMAY-03056Alias growth hormone receptor
Anti-GHR/Growth Hormone R Antibody (1X157) is a Rabbit antibody targeting GHR/Growth Hormone R. Anti-GHR/Growth Hormone R Antibody (1X157) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | growth hormone receptor |
| Ig Type | Rabbit IgG |
| Clone | 1X157 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Growth Hormone Receptor / GHR / GHBP (rM Growth Hormone Receptor / GHR / GHBP; TMPY-01448; NP_034414.2; Met1-Gln273). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Growth hormone receptor, also known as GH receptor and GHR, is a single-pass type I membrane protein which belongs to thetype I cytokine receptor family and type 1 subfamily. GHR contains onefibronectin type-III domain. Growth hormone receptor / GHR is expressed in various tissues with high expression in liver and skeletal muscle. Isoform4of GHR is predominantly expressed in kidney, bladder, adrenal gland and brain stem. Isoform1 expression of GHR in placenta is predominant in chorion and decidua. Isoform4is highly expressed in placental villi. Isoform2of GHR is expressed in lung, stomach and muscle. Growth hormone receptor / GHR is a receptor for pituitary gland growth hormone. It is involved in regulating postnatal body growth. On ligand binding, it couples to the JAK2 / STAT5 pathway. Isoform2of GHR up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling. Defects in GHR are a cause of Laron syndrome (LARS) which is a severe form of growth hormone insensitivity characterized by growth impairment, short stature, dysfunctional growth hormone receptor, and failure to generate insulin-like growth factor I in response to growth hormone. Defects in GHR may also be a cause of idiopathic short stature autosomal (ISSA) which is defined by a subnormal rate of growth. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse Growth Hormone Receptor / GHR / GHBP protein (TMPY-01448) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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