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7-O-Methyleriodictyol

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Catalog No. TN3243Cas No. 51857-11-5

7-O-Methyleriodictyol is a flavanone isolated from Artemisia monosperma and shows biological effects on rat isolated smooth muscles.

7-O-Methyleriodictyol

7-O-Methyleriodictyol

😃Good
Purity: 98.10%
Catalog No. TN3243Cas No. 51857-11-5
7-O-Methyleriodictyol is a flavanone isolated from Artemisia monosperma and shows biological effects on rat isolated smooth muscles.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$58In StockIn Stock
2 mg$79-In Stock
5 mg$138In StockIn Stock
10 mg$229-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.10%
Appearance:Solid
Color:Yellow
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
7-O-Methyleriodictyol is a flavanone isolated from Artemisia monosperma and shows biological effects on rat isolated smooth muscles.
In vitro
7-O-Methyleriodictyol (0.1 nM to 300 nM) caused concentration-dependent inhibition of the amplitude of the phasic contractions and reduced the tone of the ileum, the uterus, and the urinary bladder. 7-O-Methyleriodictyol caused relaxation of the phenylephrine-precontracted pulmonary artery and the acetylcholine-precontracted trachea. 7-O-Methyleriodictyol shifted to the right the acetylcholine concentration-effect curve on the ileum and the oxytocin concentration-effect curve on the uterus. 7-O-Methyleriodictyol inhibited the maximum contractions induced by acetylcholine or oxytocin[1].
Chemical Properties
Molecular Weight302.28
FormulaC16H14O6
Cas No.51857-11-5
SmilesO=C1C=2C(O[C@@H](C1)C3=CC(O)=C(O)C=C3)=CC(OC)=CC2O
Relative Density.1.458 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30.23 mg/mL (100.01 mM), Sonication and heating are recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.31 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3082 mL16.5410 mL33.0819 mL165.4096 mL
5 mM0.6616 mL3.3082 mL6.6164 mL33.0819 mL
10 mM0.3308 mL1.6541 mL3.3082 mL16.5410 mL
20 mM0.1654 mL0.8270 mL1.6541 mL8.2705 mL
50 mM0.0662 mL0.3308 mL0.6616 mL3.3082 mL
100 mM0.0331 mL0.1654 mL0.3308 mL1.6541 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

AChR7-O-Methyleriodictyol7OMethyleriodictyol7 O Methyleriodictyol
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