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7-O-Methyleriodictyol

🥰Excellent
Catalog No. TN3243Cas No. 51857-11-5

7-O-Methyleriodictyol is a flavanone isolated from Artemisia monosperma and shows biological effects on rat isolated smooth muscles.

7-O-Methyleriodictyol

7-O-Methyleriodictyol

🥰Excellent
Purity: 98.10%
Catalog No. TN3243Cas No. 51857-11-5
7-O-Methyleriodictyol is a flavanone isolated from Artemisia monosperma and shows biological effects on rat isolated smooth muscles.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$58In StockIn Stock
2 mg$79-In Stock
5 mg$138In StockIn Stock
10 mg$229-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.10%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
7-O-Methyleriodictyol is a flavanone isolated from Artemisia monosperma and shows biological effects on rat isolated smooth muscles.
In vitro
7-O-Methyleriodictyol (0.1 nM to 300 nM) caused concentration-dependent inhibition of the amplitude of the phasic contractions and reduced the tone of the ileum, the uterus, and the urinary bladder. 7-O-Methyleriodictyol caused relaxation of the phenylephrine-precontracted pulmonary artery and the acetylcholine-precontracted trachea. 7-O-Methyleriodictyol shifted to the right the acetylcholine concentration-effect curve on the ileum and the oxytocin concentration-effect curve on the uterus. 7-O-Methyleriodictyol inhibited the maximum contractions induced by acetylcholine or oxytocin[1].
Chemical Properties
Molecular Weight302.28
FormulaC16H14O6
Cas No.51857-11-5
SmilesO=C1C=2C(O[C@@H](C1)C3=CC(O)=C(O)C=C3)=CC(OC)=CC2O
Relative Density.1.458 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30.23 mg/mL (100.01 mM), Sonication and heating are recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.31 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3082 mL16.5410 mL33.0819 mL165.4096 mL
5 mM0.6616 mL3.3082 mL6.6164 mL33.0819 mL
10 mM0.3308 mL1.6541 mL3.3082 mL16.5410 mL
20 mM0.1654 mL0.8270 mL1.6541 mL8.2705 mL
50 mM0.0662 mL0.3308 mL0.6616 mL3.3082 mL
100 mM0.0331 mL0.1654 mL0.3308 mL1.6541 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

AChR7-O-Methyleriodictyol7OMethyleriodictyol7 O Methyleriodictyol
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