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Minamestane

Name: Minamestane
Brand: TargetMol
SKU: T71708
Price: 128 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T71708Cas No. 105051-87-4

Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes and a K of 59 nM.Minamestane has antitumor activity.

Minamestane

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Purity: 99.84%

Catalog No. T71708Cas No. 105051-87-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$128	In Stock	In Stock
5 mg	$320	In Stock	In Stock
10 mg	$470	In Stock	In Stock
25 mg	$772	In Stock	In Stock
50 mg	$1,080	In Stock	In Stock
100 mg	$1,460	In Stock	In Stock
500 mg	$2,920	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.84%

ee:100%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR ORP CSFC LCMS

Product Introduction

Bioactivity

Description	Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes and a K of 59 nM.Minamestane has antitumor activity.
Targets&IC50	Aromatase (rat ovarian):363 nM, Aromatase (human placental):369 nM

Chemical Properties

Molecular Weight	297.39
Formula	C₁₉H₂₃NO₂
Cas No.	105051-87-4
Smiles	C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)C(=O)CC4)[H])(C=CC1=C(N)C(=O)C=C2)[H])[H]

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (201.76 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3626 mL	16.8129 mL	33.6259 mL	168.1294 mL
5 mM	0.6725 mL	3.3626 mL	6.7252 mL	33.6259 mL
10 mM	0.3363 mL	1.6813 mL	3.3626 mL	16.8129 mL
20 mM	0.1681 mL	0.8406 mL	1.6813 mL	8.4065 mL
50 mM	0.0673 mL	0.3363 mL	0.6725 mL	3.3626 mL
100 mM	0.0336 mL	0.1681 mL	0.3363 mL	1.6813 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc