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Lobeline hydrochloride

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Catalog No. T0268Cas No. 134-63-4
Alias α-Lobeline hydrochloride, L-Lobeline hydrochloride

Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic receptor subtypes.

Lobeline hydrochloride
Other Forms of Lobeline hydrochloride:

Lobeline hydrochloride

🥰Excellent
Purity: 99.43%
Catalog No. T0268Alias α-Lobeline hydrochloride, L-Lobeline hydrochlorideCas No. 134-63-4
Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic receptor subtypes.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30In StockIn Stock
50 mg$44In StockIn Stock
100 mg$80In Stock-
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.43%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic receptor subtypes.
Synonymsα-Lobeline hydrochloride, L-Lobeline hydrochloride
Chemical Properties
Molecular Weight373.92
FormulaC22H27NO2·HCl
Cas No.134-63-4
SmilesCl.CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (120.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6744 mL13.3718 mL26.7437 mL133.7184 mL
5 mM0.5349 mL2.6744 mL5.3487 mL26.7437 mL
10 mM0.2674 mL1.3372 mL2.6744 mL13.3718 mL
20 mM0.1337 mL0.6686 mL1.3372 mL6.6859 mL
50 mM0.0535 mL0.2674 mL0.5349 mL2.6744 mL
100 mM0.0267 mL0.1337 mL0.2674 mL1.3372 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

α-LobelineNicotinic ReceptornAChRLobelineL-Lobelinealpha-Lobeline Hydrochloridea-Lobeline Hydrochloride
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