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Synonyms: RPOL2, RPO2, RpIILS, RPBh1, RPB1, POLRA, POLR2, hsRPB1, hRPB220
Anti-POLR2A Monoclonal Antibody
(1X991)

| Description | Anti-POLR2A Monoclonal Antibody (1X991) is a Mouse antibody targeting POLR2A. Anti-POLR2A Monoclonal Antibody (1X991) can be used in FCM. |
| Synonyms | RPOL2, RPO2, RpIILS, RPBh1, RPB1, POLRA, POLR2, hsRPB1, hRPB220 |
| Ig Type | IgG2b |
| Clone | 1X991 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human POLR2A (AA: 128-258) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | POLR2A |
| Gene ID | |
| Protein Name | DNA-directed RNA polymerase II subunit RPB1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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