β-cell

Propargite is a pesticide used to kill mites and induces β-cell necrosis preceded by DNA damage, with an IC50 of 1 μM for inducing MIN6 cell death [1].

Nateglinide (Senaglinide) is an oral hypoglycemic agent and amino acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Nateglinide has been linked to rare instances of clinically apparent acute liver injury.

Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.

ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).

GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.

NFAT inhibitor, Cell Permeable aceate is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It can be used for the research of podocyte and diabetic nephropathy.

β-Bag cell peptide, a neuroactive peptide, elevates cyclic AMP levels and reduces the amplitudes of voltage-dependent potassium currents [1] in bag cell neurons.

12-oxo-N-[1-(propan-2-yl)piperidin-4-yl]-6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide available as a molecular structural unit, it is used in the synthesis of various compounds.

γ-Bag cell peptide, a peptide situated near the N-terminus of the egg-laying prohormone, is released from vesicles upon insulin stimulation. It is utilized in research pertaining to both the central and peripheral nervous systems [1].

α-Bag Cell Peptide (1-8) is an NH2-terminal fragment of α-bag cell peptide that inhibits LUQ (left upper quadrant) neurons and the depolarization of bag cells [1].

α-Bag Cell Peptide (1-7) is an amino-terminal fragment of the α-bag cell peptide that possesses the ability to inhibit neurons in the left upper quadrant (LUQ) and prevent the depolarization of the bag cells [1].

Anti-Mouse Pan-endothelial Cell Antigen/MECA-32 Antibody (MECA-32) is an IgG2a, κ antibody inhibitor derived from rats, targeting the mouse Pan-endothelial Cell Antigen/MECA-32.

Anti-iNKT Cell Antibody (6B11) is an antibody targeting iNKT Cell and can be used for immunology research.

Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.

Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.

Mast cell degranulating peptide (28-49) is a bee venom depolarizer that enhances cGMP levels in cerebellum tablets of mice.

α-Bag Cell Peptide (1-9) is a polypeptide molecule with the sequence APRLRFYSL.

HexokinaseIIVDACbinding domain peptide (Hxk2VBD peptide) is a cell-permeable peptide derived from the hexokinase II VDAC binding domain. This peptide inhibits the mitochondrial localization of hexokinase 2 (HXK2) and also suppresses neurotrophic factor-induced axon growth.

Activable cell-penetrating peptide (ACCP) consists of a polycationic CPP, typically arg9 or r9, linked to a matching polyanion, usually glu9 or e9, via a cleavable linker. This connection reduces the net charge to nearly zero, thereby inhibiting adhesion and uptake into cells.

JNK-IN-15, Cell-Permeable (JNK inhibitor III), is an inhibitor of JNK. It is applicable in the research of age-related neurodegenerative diseases.

JNK-IN-15, Cell-Permeable, Negative Control serves as the negative control for JNK-IN-15, Cell-Permeable. JNK-IN-15, Cell-Permeable functions as an inhibitor of JNK.

Iron(III) nitrate nonahydrate, for cell culture (Ferric nitrate nonahydrate, for cell culture), is a compound suitable for use in cell culture applications.

Iron (III) sulfate hydrate,for plant cell culture is a reagent used in biochemical reactions.

MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, leading to accumulation of LC3II proteins and increased autophagosomes, thereby inhibiting cellular autophagy.