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Anti-CD166/ALCAM Antibody (7F950)
(Synonyms: MEMD, CD166, activated leukocyte cell adhesion molecule) Copy Product Info
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Synonyms: MEMD, CD166, activated leukocyte cell adhesion molecule
Catalog No. TMAY-03777 Copy Product Info
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Anti-CD166/ALCAM Antibody (7F950) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (7F950) can be used in ELISA,IP,WB.
Anti-CD166/ALCAM Antibody
(7F950)
(7F950)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD166/ALCAM Antibody (7F950) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (7F950) can be used in ELISA,IP,WB. |
| Synonyms | MEMD, CD166, activated leukocyte cell adhesion molecule |
| Ig Type | Rabbit IgG |
| Clone | 7F950 |
| Reactivity | Rat |
| Specificity | Rat CD166/ALCAM Has cross-reactivity in ELISA with Human ALCAM No cross-reactivity in ELISA with Human BCAM |
| Application | |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IP: 1-4 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD166 / ALCAM (TMPY-02936; O35112; Met1-Lys527). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat CD166 / ALCAM protein (TMPY-02936) |
| Antigen Species | Rat |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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