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Anti-CD166/ALCAM Antibody (5E235) (Synonyms: MEMD, CD166, activated leukocyte cell adhesion molecule)
Catalog No. TMAY-03905 Copy Product Info
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Anti-CD166/ALCAM Antibody (5E235) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5E235) can be used in WB.
Anti-CD166/ALCAM Antibody (5E235)
Copy Product Info🥰Excellent
Catalog No. TMAY-03905
Synonyms MEMD, CD166, activated leukocyte cell adhesion molecule
Anti-CD166/ALCAM Antibody (5E235) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5E235) can be used in WB.
Anti-CD166/ALCAM Antibody
(5E235)
(5E235)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
Related Conjugates and Formulations
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| Description | Anti-CD166/ALCAM Antibody (5E235) is a Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody (5E235) can be used in WB. |
| Synonyms | MEMD, CD166, activated leukocyte cell adhesion molecule |
| Ig Type | Rabbit IgG |
| Clone | 5E235 |
| Reactivity | Cynomolgus |
| Specificity | Cynomolgus CD166/ALCAM |
| Verified Activity | Anti-ALCAM rabbit monoclonal antibody at 1:500 dilution. -Lane A: HuT78 Whole Cell Lysate. -Lane B: Daudi Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:65 kDa. -Observed band size:65 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus CD166 / ALCAM (TMPY-03520; G7NZQ8; Met1-Ala526). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Cynomolgus CD166 / ALCAM protein (TMPY-03520) |
| Antigen Species | Cynomolgus |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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