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5,7-Dichlorokynurenic acid

Name: 5,7-Dichlorokynurenic acid
Brand: TargetMol
SKU: T22517
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22517Cas No. 131123-76-7

Alias 5,7-dichlorokynurenic acid sodium, 5,7-DCKA

5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.

5,7-Dichlorokynurenic acid

🥰Excellent

Purity: 99.71%

Catalog No. T22517Alias 5,7-dichlorokynurenic acid sodium, 5,7-DCKACas No. 131123-76-7

5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.

Pack Size	Price	Availability
5 mg	$39	In Stock
10 mg	$68	In Stock
25 mg	$148	In Stock
50 mg	$259	In Stock
100 mg	$387	In Stock
500 mg	$897	In Stock

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Batch Information

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Purity:99.71%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.
Synonyms	5,7-dichlorokynurenic acid sodium, 5,7-DCKA

Chemical Properties

Molecular Weight	258.06
Formula	C₁₀H₅Cl₂NO₃
Cas No.	131123-76-7
Smiles	OC(=O)c1cc(O)c2c(Cl)cc(Cl)cc2n1
Relative Density.	1.701 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (213.13 mM), Sonication is recommended.

1eq. NaOH: 100 mM, Sonication is recommended.

Solution Preparation Table

1eq. NaOH/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8751 mL	19.3753 mL	38.7507 mL	193.7534 mL
5 mM	0.7750 mL	3.8751 mL	7.7501 mL	38.7507 mL
10 mM	0.3875 mL	1.9375 mL	3.8751 mL	19.3753 mL
20 mM	0.1938 mL	0.9688 mL	1.9375 mL	9.6877 mL
50 mM	0.0775 mL	0.3875 mL	0.7750 mL	3.8751 mL
100 mM	0.0388 mL	0.1938 mL	0.3875 mL	1.9375 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc