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Anti-ESAM Antibody-FITC (4F225) (Synonyms: endothelial cell adhesion molecule)
Catalog No. TMAY-00424F Copy Product Info
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Anti-ESAM Antibody-FITC (4F225) is a FITC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-FITC (4F225) can be used in FCM.
Anti-ESAM Antibody-FITC (4F225)
Copy Product Info🥰Excellent
Catalog No. TMAY-00424F
Synonyms endothelial cell adhesion molecule
Anti-ESAM Antibody-FITC (4F225) is a FITC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-FITC (4F225) can be used in FCM.
Anti-ESAM Antibody-FITC
(4F225)
(4F225)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 T | $104 | 7-10 days | 7-10 days | |
| 100 T | $211 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-ESAM Antibody-FITC (4F225) is a FITC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-FITC (4F225) can be used in FCM. |
| Synonyms | endothelial cell adhesion molecule |
| Ig Type | Rabbit IgG |
| Clone | 4F225 |
| Reactivity | Human |
| Specificity | Human ESAM |
| Verified Activity | Profile of anti-ESAM reactivity on HUVEC cells analyzed by flow cytometry. |
| Application | |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ESAM (rh ESAM; TMPY-01312; NP_620411.2; Met 1-Ala 248) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth. |
| Conjucates | FITC |
| Others Formats | Unconjugated/APC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human ESAM protein (TMPY-01312) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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